SAFETY DATA SHEET according to Regulation (EC) No. 1907/2006 Version 3.0 Revision Date 25.12.2008 Print Date 21.01.2010 GENERIC EU MSDS - NO COUNTRY SPECIFIC DATA - NO OEL DATA 1. IDENTIFICATION OF THE SUBSTANCE/PREPARATION AND OF THE COMPANY/UNDERTAKING Product name : 2',4'-Dichloro-5'-hydroxyacetanilide Product Number : 655880 Brand : Aldrich Company : Sigma-Aldrich (Shanghai) Trading Co.,Ltd 22A-B Century Ba-Shi Building, 398 Huai Hai Zhong Road 200020 SHANGHAI CHINA Telephone : +862161415566 Fax : +862161415567 Emergency Phone # : E-mail address : china@sial.com 2. HAZARDS IDENTIFICATION Risk advice to man and the environment Toxic if swallowed. Irritating to eyes, respiratory system and skin. 3. COMPOSITION/INFORMATION ON INGREDIENTS Synonyms : 5-Acetylamino-2,4-dichlorophenol Formula : C8H7Cl2NO2 Molecular Weight : 220,05 g/mol CAS-No. EC-No. Index-No. Classification Concentration 2',4'-Dichloro-5'-hydroxyacetanilide 67669-19-6 - - T, R25 - R36/37/38 - 4. FIRST AID MEASURES General advice Consult a physician. Show this safety data sheet to the doctor in attendance. If inhaled If breathed in, move person into fresh air. If not breathing give artificial respiration Consult a physician. In case of skin contact Wash off with soap and plenty of water. Consult a physician. In case of eye contact Rinse thoroughly with plenty of water for at least 15 minutes and consult a physician. If swallowed Never give anything by mouth to an unconscious person. Rinse mouth with water. Consult a physician. 5. FIRE-FIGHTING MEASURES Suitable extinguishing media Use water spray, alcohol-resistant foam, dry chemical or carbon dioxide. Special protective equipment for fire-fighters Wear self contained breathing apparatus for fire fighting if necessary. 6. ACCIDENTAL RELEASE MEASURES Personal precautions Use personal protective equipment. Avoid dust formation. Avoid breathing dust. Ensure adequate ventilation. Evacuate personnel to safe areas. Environmental precautions Prevent further leakage or spillage if safe to do so. Do not let product enter drains. Methods for cleaning up Pick up and arrange disposal without creating dust. Keep in suitable, closed containers for disposal. 7. HANDLING AND STORAGE Handling Avoid contact with skin and eyes. Avoid formation of dust and aerosols. Provide appropriate exhaust ventilation at places where dust is formed. Normal measures for preventive fire protection. Storage Store in cool place. Keep container tightly closed in a dry and well-ventilated place. 8. EXPOSURE CONTROLS/PERSONAL PROTECTION Personal protective equipment Respiratory protection Where risk assessment shows air-purifying respirators are appropriate use a full-face particle respirator type N99 (US) or type P2 (EN 143) respirator cartridges as a backup to engineering controls. If the respirator is the sole means of protection, use a full-face supplied air respirator. Use respirators and components tested and approved under appropriate government standards such as NIOSH (US) or CEN (EU). Hand protection The selected protective gloves have to satisfy the specifications of EU Directive 89/686/EEC and the standard EN 374 derived from it. Handle with gloves. Eye protection Safety glasses Skin and body protection Choose body protection according to the amount and concentration of the dangerous substance at the work place. Hygiene measures Avoid contact with skin, eyes and clothing. Wash hands before breaks and immediately after handling the product. 9. PHYSICAL AND CHEMICAL PROPERTIES Appearance Form solid Safety data pH no data available Melting point 233 - 236 ˇăC Boiling point no data available Flash point no data available Ignition temperature no data available Lower explosion limit no data available Upper explosion limit no data available Water solubility no data available Partition coefficient: n-octanol/water log Pow: 2,54 10. STABILITY AND REACTIVITY Storage stability Stable under recommended storage conditions. Materials to avoid Strong oxidizing agents Hazardous decomposition products Hazardous decomposition products formed under fire conditions. - Carbon oxides, nitrogen oxides (NOx), Hydrogen chloride gas 11. TOXICOLOGICAL INFORMATION Acute toxicity no data available Irritation and corrosion no data available Sensitisation no data available Chronic exposure IARC: No component of this product present at levels greater than or equal to 0.1% is identified as probable, possible or confirmed human carcinogen by IARC. Potential Health Effects Inhalation May be harmful if inhaled. Causes respiratory tract irritation. Skin May be harmful if absorbed through skin. Causes skin irritation. Eyes Causes eye irritation. Ingestion Toxic if swallowed. 12. ECOLOGICAL INFORMATION E limination information (persistence and degradability) no data available E cotoxicity effects no data available Further information on ecology no data available 13. DISPOSAL CONSIDERATIONS Product Observe all federal, state, and local environmental regulations. Contact a licensed professional waste disposal service to dispose of this material. Dissolve or mix the material with a combustible solvent and burn in a chemical incinerator equipped with an afterburner and scrubber. Contaminated packaging Dispose of as unused product. 14. TRANSPORT INFORMATION ADR/RID UN-Number: 2811 Class: 6.1 Packing group: III Proper shipping name: TOXIC SOLID, ORGANIC, N.O.S. (2',4'-Dichloro-5'-hydroxyacetanilide) IMDG UN-Number: 2811 Class: 6.1 Packing group: III EMS-No: F-A, S-A Proper shipping name: TOXIC SOLID, ORGANIC, N.O.S. (2',4'-Dichloro-5'-hydroxyacetanilide) Marine pollutant: No IATA UN-Number: 2811 Class: 6.1 Packing group: III Proper shipping name: Toxic solid, organic n.o.s. (2',4'-Dichloro-5'-hydroxyacetanilide) 15. REGULATORY INFORMATION Labelling according to EC Directives Hazard symbols T Toxic R-phrase(s) R25 Toxic if swallowed. R36/37/38 Irritating to eyes, respiratory system and skin. S-phrase(s) S26 In case of contact with eyes, rinse immediately with plenty of water and seek medical advice. S36 Wear suitable protective clothing. S45 In case of accident or if you feel unwell, seek medical advice immediately (show the label where possible). 16. OTHER INFORMATION Further information Copyright 2008 Sigma-Aldrich Co. License granted to make unlimited paper copies for internal use only. The above information is believed to be correct but does not purport to be all inclusive and shall be used only as a guide. The information in this document is based on the present state of our knowledge and is applicable to the product with regard to appropriate safety precautions. It does not represent any guarantee of the properties of the product. Sigma-Aldrich Co., shall not be held liable for any damage resulting from handling or from contact with the above product. See reverse side of invoice or packing slip for additional terms and conditions of sale.